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USC-OGP 2-DE database
Two-dimensional polyacrylamide gel electrophoresis database
USC-OGP 2-DE database
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Searching in 'USC-OGP 2-DE database' for entry
matching:
MVP_HUMAN
USC-OGP 2-DE database
:
MVP_HUMAN
MVP_HUMAN
General information about the entry
View entry in simple text format
Entry name
MVP_HUMAN
Primary accession number
Q14764
integrated into USC-OGP 2-DE database on
January 17, 2017 (release 1)
2D Annotations were last modified on
January 17, 2017 (version 1)
General Annotations were last modified on
April 5, 2017 (version 2)
Name and origin of the protein
Description
RecName: Full=Major vault protein; Short=MVP; AltName: Full=Lung resistance-related protein;.
Gene name
Name=MVP
Synonyms=LRP
Annotated species
Homo sapiens (Human) [TaxID:
9606
]
Taxonomy
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo.
References
[1]
2D GEL CHARACTERIZATION
Author 1., Author 2.
Submitted (Mar-2011) to Current
2D PAGE maps for identified proteins
How to interpret a protein
PLATELET_4-7
{PLATELET 4-7}
Homo sapiens (Human)
map experimental info
PLATELET_4-7
MAP LOCATIONS:
SPOT OGP-0273
:
pI=5.27; Mw=131482
UVEAL_MELANOMA_3-10
{UVEAL MELANOMA 3-10}
Homo sapiens (Human)
map experimental info
UVEAL_MELANOMA_3-10
MAP LOCATIONS:
SPOT OGP-1101
:
pI=5.44; Mw=126814
Cross-references
UniProtKB/Swiss-Prot
Q14764; MVP_HUMAN.
2D PAGE maps for identified proteins
How to interpret a protein map
You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw.
Warning 1
: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly.
Warning 2
: the 2D PAGE map is built on demand. This may take some few seconds to be computed.
External data extracted from
UniProtKB/Swiss-Prot
Extracted from
UniProtKB/Swiss-Prot
, release:
0.0
Entry name
MVP_HUMAN
Primary accession number
Q14764
Secondary accession number(s)
Q96BG4 Q9BPW6 Q9BQT1 Q9UBD1
Sequence was last modified on
January 23, 2007 (version 4)
Annotations were last modified on
March 15, 2017 (version 158)
Name and origin of the protein
Description
RecName: Full=Major vault protein; Short=MVP; AltName: Full=Lung resistance-related protein;
Gene name
Name=MVP
Synonyms=LRP
Encoded on
Name=MVP; Synonyms=LRP
Keywords
3D-structure
;
Acetylation
;
Complete proteome
;
Cytoplasm
;
Direct protein sequencing
;
Isopeptide bond
;
mRNA transport
;
Nuclear pore complex
;
Nucleus
;
Phosphoprotein
;
Polymorphism
;
Protein transport
;
Reference proteome
;
Repeat
;
Ribonucleoprotein
;
Translocation
;
Transport
;
Ubl conjugation
.
Copyright
Copyrighted by the UniProt Consortium, see
http://www.uniprot.org/help/license
. Distributed under the Creative Commons Attribution-NoDerivs License
Cross-references
EMBL
X79882; CAA56256.2
; -; mRNA
EMBL
BC015623; AAH15623.1
; -; mRNA
EMBL
AJ238512; CAB55354.1
; -; Genomic_DNA
EMBL
AJ238514; CAB55354.1
; JOINED; Genomic_DNA
EMBL
AJ238516; CAB55354.1
; JOINED; Genomic_DNA
EMBL
AJ238518; CAB55354.1
; JOINED; Genomic_DNA
EMBL
AJ238519; CAB55355.1
; -; Genomic_DNA
EMBL
AJ238514; CAB55355.1
; JOINED; Genomic_DNA
EMBL
AJ238516; CAB55355.1
; JOINED; Genomic_DNA
EMBL
AJ238518; CAB55355.1
; JOINED; Genomic_DNA
EMBL
AJ291365; CAC35313.1
; -; Genomic_DNA
EMBL
AJ291366; CAC35314.1
; -; mRNA
EMBL
AJ291367; CAC35316.1
; -; mRNA
CCDS
CCDS10656.1; -
; .
PIR
S57723; S57723
; .
RefSeq
NP_001280133.1; NM_001293204.1
; .
RefSeq
NP_001280134.1; NM_001293205.1
; .
RefSeq
NP_005106.2; NM_005115.4
; .
RefSeq
NP_059447.2; NM_017458.3
; .
UniGene
Hs.632177; -
; .
PDB
1Y7X; NMR
; -; A=113-221
PDBsum
1Y7X; -
; .
ProteinModelPortal
Q14764; -
; .
SMR
Q14764; -
; .
BioGrid
115286; 93
; .
IntAct
Q14764; 39
; .
MINT
MINT-5004583; -
; .
STRING
9606.ENSP00000349977; -
; .
TCDB
1.I.1.1.3; the nuclear pore complex (npc) family
; .
iPTMnet
Q14764; -
; .
PhosphoSitePlus
Q14764; -
; .
SwissPalm
Q14764; -
; .
BioMuta
MVP; -
; .
DMDM
21542417; -
; .
OGP
Q14764; -
; .
REPRODUCTION-2DPAGE
IPI00000105; -
; .
EPD
Q14764; -
; .
PaxDb
Q14764; -
; .
PeptideAtlas
Q14764; -
; .
PRIDE
Q14764; -
; .
DNASU
9961; -
; .
Ensembl
ENST00000357402; ENSP00000349977
; ENSG00000013364; .
Ensembl
ENST00000395353; ENSP00000378760
; ENSG00000013364; .
GeneID
9961; -
; .
KEGG
hsa:9961; -
; .
CTD
9961; -
; .
DisGeNET
9961; -
; .
GeneCards
MVP; -
; .
HGNC
HGNC:7531; MVP
; .
HPA
CAB002752; -
; .
HPA
CAB022717; -
; .
HPA
HPA002321; -
; .
HPA
HPA064740; -
; .
MIM
605088; gene
; .
neXtProt
NX_Q14764; -
; .
OpenTargets
ENSG00000013364; -
; .
PharmGKB
PA31332; -
; .
eggNOG
ENOG410IF6T; Eukaryota
; .
eggNOG
ENOG410ZCU8; LUCA
; .
GeneTree
ENSGT00390000008969; -
; .
HOGENOM
HOG000255109; -
; .
HOVERGEN
HBG003499; -
; .
InParanoid
Q14764; -
; .
KO
K17266; -
; .
OMA
NKGQDPL; -
; .
OrthoDB
EOG091G032A; -
; .
PhylomeDB
Q14764; -
; .
TreeFam
TF329353; -
; .
Reactome
R-HSA-6798695; Neutrophil degranulation
; .
SignaLink
Q14764; -
; .
EvolutionaryTrace
Q14764; -
; .
GeneWiki
Major_vault_protein; -
; .
GenomeRNAi
9961; -
; .
PRO
PR:Q14764; -
; .
Proteomes
UP000005640; Chromosome 16
; .
Bgee
ENSG00000013364; -
; .
CleanEx
HS_MVP; -
; .
ExpressionAtlas
Q14764; baseline and differential
; .
Genevisible
Q14764; HS
; .
GO
GO:0005737; C:cytoplasm
; IDA:UniProtKB; .
GO
GO:0005856; C:cytoskeleton
; IDA:UniProtKB; .
GO
GO:0005829; C:cytosol
; IDA:HPA; .
GO
GO:0070062; C:extracellular exosome
; IDA:UniProtKB; .
GO
GO:0005576; C:extracellular region
; TAS:Reactome; .
GO
GO:1904813; C:ficolin-1-rich granule lumen
; TAS:Reactome; .
GO
GO:0030529; C:intracellular ribonucleoprotein complex
; IEA:UniProtKB-KW; .
GO
GO:0016020; C:membrane
; IDA:UniProtKB; .
GO
GO:0005643; C:nuclear pore
; IEA:UniProtKB-SubCell; .
GO
GO:0005634; C:nucleus
; IDA:UniProtKB; .
GO
GO:0048471; C:perinuclear region of cytoplasm
; IDA:UniProtKB; .
GO
GO:0034774; C:secretory granule lumen
; TAS:Reactome; .
GO
GO:0042802; F:identical protein binding
; IPI:IntAct; .
GO
GO:0019901; F:protein kinase binding
; IPI:UniProtKB; .
GO
GO:0019903; F:protein phosphatase binding
; IDA:UniProtKB; .
GO
GO:0038127; P:ERBB signaling pathway
; IDA:UniProtKB; .
GO
GO:0051028; P:mRNA transport
; IEA:UniProtKB-KW; .
GO
GO:0031953; P:negative regulation of protein autophosphorylation
; IDA:UniProtKB; .
GO
GO:0061099; P:negative regulation of protein tyrosine kinase activity
; IDA:UniProtKB; .
GO
GO:0023057; P:negative regulation of signaling
; IDA:UniProtKB; .
GO
GO:0043312; P:neutrophil degranulation
; TAS:Reactome; .
GO
GO:0015031; P:protein transport
; IEA:UniProtKB-KW; .
CDD
cd08825; MVP_shoulder
; 1; .
InterPro
IPR021870; MVP_shoulder
; .
InterPro
IPR002499; Vault_N
; .
Pfam
PF11978; MVP_shoulder
; 1; .
Pfam
PF01505; Vault
; 4; .
PROSITE
PS51224; MVP
; 8; .
Gateways to other related servers
The World-2DPAGE Constellation
- Entry point to the world-wide 2-DPAGE resources.
World-2DPAGE Repository
- A public repository for gel-based proteomics data linked to protein identification published in the literature.
World-2DPAGE Portal
- A dynamic portal to query simultaneously world-wide gel-based proteomics databases.
SWISS-2DPAGE
- The Geneva Two-dimensional polyacrylamide gel electrophoresis database.
ExPASy
- The resources web server of the
Swiss Institute of Bioinformatics
Database constructed and maintained by
Angel Garcia
, using the
Make2D-DB II
package (
ver. 3.10.2
) from the
World-2DPAGE Constellation
of the
ExPASy web server
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